[Biomathematics & Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/) programs reward a close look at where your money goes furthest. The best values balance affordable tuition against strong post-graduation earnings.
To produce this 2026 ranking, College Factual evaluated 11 schools on the balance of cost and outcomes for biomathematics & bioinformatics students.
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Below are the schools that deliver the strongest value in biomathematics & bioinformatics, balancing cost against outcomes.
For return on investment in biomathematics & bioinformatics, no school beat University Of Pittsburgh Pittsburgh Campus this year. Located in the city of Pittsburgh, University Of Pittsburgh Pittsburgh Campus is a very large public university. Expect in-state tuition and fees of around $21,926, with out-of-state students paying around $41,430. Biomathematics & Bioinformatics graduates carry a median of $24,958 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of Pittsburgh Pittsburgh Campus generally make around $56,926. Weighed against typical debt, the earnings make a compelling case for value. The acceptance rate is 58%.
A rank of #2 makes University Of Pennsylvania one of the best values for biomathematics & bioinformatics. University Of Pennsylvania is a very large private not-for-profit school located in the city of Philadelphia. The average in-state cost of tuition and fees is $68,686. Typical student debt for biomathematics & bioinformatics graduates is $16,155. Early-career biomathematics & bioinformatics graduates make about $99,682. Weighed against typical debt, the earnings make a compelling case for value. University Of Pennsylvania admits about 5% of applicants.
Students looking for strong value in biomathematics & bioinformatics will find it at Carnegie Mellon University, which ranked #3. Carnegie Mellon University is a large private not-for-profit school located in the city of Pittsburgh. Expect in-state tuition and fees of around $65,636. Biomathematics & Bioinformatics graduates carry a median of $23,529 in student loans. Biomathematics & Bioinformatics graduates of Carnegie Mellon University earn a median of $89,327 early in their careers. Set against $23,529 in median debt, that is a healthy payoff. Carnegie Mellon University admits about 12% of applicants.
Drexel University is a great value for students pursuing a degree in biomathematics & bioinformatics, landing the #4 spot this year. Drexel University is a very large private not-for-profit school located in the city of Philadelphia. In-state tuition and fees average $62,412. Students borrow a median of $28,838 to complete the biomathematics & bioinformatics program here. Biomathematics & Bioinformatics graduates of Drexel University earn a median of $67,556 early in their careers. That is a strong return on a $28,838 median debt. The acceptance rate is 79%.
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Notes and References
This list is compiled by College Factual (MF_RANKING_2025), 2026 edition. Schools are scored on the balance of cost (tuition and student debt) against student outcomes (post-graduation earnings) — a measure of return on investment, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 11 schools evaluated.
*Averages shown above reflect the top 2 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
